Rational Prescription of Drug in Iran: Statistics and Trends for Policymakers
Background: Medicine is considered as strategic goods worldwide and, therefore, a huge
amount of health care budget is spent on it. To prepare universal access to appropriate health services and achieve the health-related millennium development goals, rational use of drugs is an essential goal in the health system. This study aimed to investigate the proportion of drug prescription in three categories of injections, antibacterials agents and corticosteroids in a 10 year period.
Methods: This is a descriptive study using data from an Iranian national insurance
organization and National Center of Drug Use. The data about prescribed drugs during 2003
to 2013 were collected and analyzed by Excel Microsoft software, version 2010.
Result: Results indicated that injections were decreased from 49.25% in 2003 to 46% in 2013;also, antimicrobials had a decrease from 64.25% in 2003 to 42.2% in 2013. Totally, it was reduced about 16% in the period of 10 years. Corticosteroids increased 10 % from 13% to 23% in 2013.
Conclusion: According the present findings that indicate irrational and increasing use of
corticosteroids and antimicrobials, it seems necessary for Iranian policy makers to pay specific attention to customizing clinical and pharmaceutical guidelines along with improvement of medical education system and rational prescription, holding scientific committees of prescription supervision, arranging continuous and effective education of health personnel, and improving public culture and community education.
Keywords: Injections, Antimicrobials, Rational prescribing
Akl OA, El Mahalli AA, Elkahky AA, Salem AM.
WHO/INRUD drug use indicators at primary
healthcare centers in Alexandria, Egypt. Journal of
Taibah University Medical Sciences. 2014;9(1):54-
Bachhav SS, Kshirsagar NA. Systematic review
of drug utilization studies & the use of the
drug classification system in the WHO-SEARO
Region. Indian J Med Res. 2015;142(2):120-9. doi:
Mao W, Vu H, Xie Z, Chen W, Tang S. Systematic
review on irrational use of medicines in China
and Vietnam. PLoS One. 2015;10(3):e0117710.
Soleymani F, Ahmadizar F, Meysamie A,
Abdollahi M. A survey on the factors influencing
the pattern of medicine’s use: Concerns on
irrational use of drugs. Journal of research
in pharmacy practice. 2013;2(2):59-63. doi:
Kumar S. A study on drug use pattern using
who prescribing indicators in in-patients of
medicine department in a rural tertiary care
teaching hospital. Indo American Journal of Pham
Zhang X, Wang L, Zhang X. Application of
propensity scores to explore the effect of public
reporting of medicine use information on
rational drug use in China: a quasi-experimental
design. BMC Health Serv Res. 2014;14:492. doi:
Rong F. Configuration Center irrational drug use
intravenous drugs analysis. Inner Mongolia Journal
of Traditional Chinese Medicine. 2013;22:103.
Uzochukwu BS, Onwujekwe OE, Okwuosa C, Ibe
OP. Patent medicine dealers and irrational use of
medicines in children: the economic cost and
implications for reducing childhood mortality
in southeast Nigeria. PLoS One. 2014;9(3):e91667.
Bastani P, Mehralian G, Dinarvand R. Resource
allocation and purchasing arrangements to
improve accessibility of medicines: Evidence
from Iran. J Res Pharm Pract. 2015;4(1):9-17. doi:
Teymourzadeh E, Rashidian A, Arab M, Akbari-
Sari A, Hakimzadeh SM. Nurses exposure to
workplace violence in a large teaching hospital in
Iran. Int J Health Policy Manag. 2014;3(6):301-5.
Bahadori M, Babashahy S, Teymourzadeh E,
Hakimzadeh SM. Activity based costing in
health care center: A case study of Iran. African
Journal of Business Management. 2012;6(6):2181.
Wondimu A, Molla F, Abrha S, Mohammed J,
Demeke B, Eticha T, et al. Drug Use during Acute
Illness in Tigray Region, Northern Ethiopia: A
Household Study. PLoS One. 2015;10(12):e0145007.
Banerjee I, Bhadury T, Sengupta T, Roy D. Drug
Utilization Study in Ophthalmology Out-patient
Department of a Medical College in India.
Ann Med Health Sci Res. 2014;4(4):667-70. doi:
Soleymani F, Haerizadeh M, Farshchi A.
Economic burden of irrational use of injectable
form of Dexamethasone: a warning to health
system. Journal of Pharmacoeconomics and
Pharmaceutical Management. 2015;1(3/4):56-8.
Desalegn AA. Assessment of drug use pattern
using WHO prescribing indicators at Hawassa
University Teaching and Referral Hospital, south
Ethiopia: a cross-sectional study. BMC Health Serv
Res. 2013;13:170. doi: 10.1186/1472-6963-13-170
Mosleh A. Drug prescription based on WHO
indicators&58; Tehran university of medical
sciences facilities with pharmacy. Tehran University
Medical Journal. 2007;65(A00101s1):12-5.
Sepehri G, Talebizadeh N, Mirzazadeh A, Mirshekari
T-R, Sepehri E. Bacterial contamination
and resistance to commonly used antimicrobials
of healthcare workers’ mobile phones in
teaching hospitals, Kerman, Iran. Am J Appl Sci.
;6(5):806-10. doi: 10.3844/ajassp.2009.806.810
Zare N, Razm jM, Ghaemi nM, Zeyghami B,
Agha MZ. Effectiveness of the feedback and
recalling education on quality of prescription by
general practitioners in Shiraz. Zahedan Journal
of Research in Medical Sciences (Tabib-E-Shargh).
Bashrahil K. Indicators of rational drug use and
health services in Hadramout, Yemen/Indicateurs
d’usage rationnel des medicaments et des services
de sante dans le gouvernorat d’Hadramout
(Yemen). East Mediterr Health J. 2010;16(2):151.
Mankadavath A, Chandrasekhar D, Thomas T,
Zuhra F, Kaipanthodi S, Parambil JC. A prospective
drug use evaluation of antihypertensive drugs in
in-patients of a tertiary referral care hospital. J
Basic Clin Physiol Pharmacol. 2015;26(3):295-
Shah A, Jan SU. Irrational Drug Use Pattern In
Hospitals. A Warning for Health Care System.
Value Health. 2015;18(7):A566. doi: 10.1016/j.
Bao L, Wang Y, Shang T, Ren X, Ma R. A novel
clinical pharmacy management system in
improving the rational drug use in department of
general surgery. Indian J Pharm Sci. 2013;75(1):11-
Sharif S, Al-Shaqra M, Hajjar H, Shamout A,
Wess L. Patterns of drug prescribing in a hospital
in dubai, United arab emirates. Libyan J Med.
;3(1):10-2. doi: 10.4176/070928
Tan E, Akıncı A, Ayvaz G, Erbaş T, Ertaş M, Güç
O, et al. Irrational drug use in neuropathic pain
treatment: a twoyear data analysis. International
Journal of Medicine and Biomedical Research.
;2(3):202-6. doi: 10.14194/ijmbr.237
Lukali V, Michelo C. Factors associated with
irrational drug use at a district hospital in
Zambia: patient record-based observations. Med
J Zambia. 2015;42(1):25-30.
Farrugia A. Assembling the dominant accounts
of youth drug use in Australian harm reduction
drug education. Int J Drug Policy. 2014;25(4):663-
Gadde L-E, Håkansson H. The changing role of
purchasing: reconsidering three strategic issues.
European Journal of Purchasing & Supply Management.
;1(1):27-35. doi: 10.1016/0969-7012(94)90040-x
Mohagheghi MA, Mosavi-Jarrahi A, Khatemi-
Moghaddam M, Afhami S, Khodai S, Azemoodeh
O. Community-based outpatient practice of
antibiotics use in Tehran. Pharmacoepidemiol
Drug Saf. 2005;14(2):135-8. doi: 10.1002/pds.1057
Hakimzadeh SM, Shokouh H, Morteza S, Bahadori
M, Tahernezhad K. Research Needs Assessment
and Priority Setting for Health Economics: A
Mixed method Study in Iran. Journal Mil Med.
Tavana AM, Hatamlo H, Teymourzadeh E,
Ebrahimnia M, Tofighi S, Bahadori M, et al.
Determining research priorities based on four
main areas: Stewardship, Creating resources,
Financing and Delivering services in health
care system in Iran. Journal of Health Policy and
Sustainable Health. 2015;2(1).
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution 3.0 License.
pISSN: 2322-1097 eISSN: 2423-5857